abstract：OBJECTIVE:Acute pulmonary embolism (PE) is a life-threatening disorder with high mortality. A prompt diagnosis and treatment is essential for reducing the mortality rate. The purpose of the study is to evaluate if lung perfusion scintigraphy (LPS) continues to have a role in the clinical management of patients suspecte...

journal_title：Annals of nuclear medicine

authors： Koukouraki SI,Hatzidakis AA,Mitrouska I,Stathaki MI,Perisinakis K

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Radium-223 (223Ra) is used in unsealed radionuclide therapy for metastatic bone tumors. The aim of this study is to apply a computational model observer to 223Ra planar images, and to assess the performance of collimators in 223Ra imaging. METHODS:The 223Ra planar images were created via an in-house Monte Ca...

journal_title：Annals of nuclear medicine

authors： Takahashi A,Baba S,Sasaki M

更新日期：2018-12-01 00:00:00

abstract：:Written by associate editors of the Annals of Nuclear Medicine, this invited review article is intended to offer our readers a condensed global view on the high-quality research work that has been published in Europe last year. We have divided this article into five sections. The first three sections from the oncology...

journal_title：Annals of nuclear medicine

authors： Inubushi M,Tatsumi M,Yamamoto Y,Kato K,Tsujikawa T,Nishii R

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to perform a systematic review of the prognostic value of texture parameters derived by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with lung cancer. METHODS:PubMed and EMBASE databases were searched up to March 12, 2018, for original articles invol...

journal_title：Annals of nuclear medicine

authors： Han S,Woo S,Suh CH,Kim YJ,Oh JS,Lee JJ

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Primary brain lymphoma is an aggressive extranodal non-Hodgkin lymphoma with poor prognosis. Many possible prognostic factors are investigated with controversial results, but possible prognostic role of 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) features re...

journal_title：Annals of nuclear medicine

authors： Albano D,Bertoli M,Battistotti M,Rodella C,Statuto M,Giubbini R,Bertagna F

更新日期：2018-10-01 00:00:00

abstract：AIM:To assess the predictive and prognostic value of textural parameters in locally advanced breast cancer (LABC) obtained by 18F-FDG PET/CT. METHODS:Prospective study including 68 patients with LABC, neoadjuvant chemotherapy (NC) indication and a baseline 18F-FDG PET/CT. Breast specimens were grouped into molecular p...

journal_title：Annals of nuclear medicine

authors： Molina-García D,García-Vicente AM,Pérez-Beteta J,Amo-Salas M,Martínez-González A,Tello-Galán MJ,Soriano-Castrejón Á,Pérez-García VM

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:An artificial neural network (ANN) has been applied to detect myocardial perfusion defects and ischemia. The present study compares the diagnostic accuracy of a more recent ANN version (1.1) with the initial version 1.0. METHODS:We examined 106 patients (age, 77 ± 10 years) with coronary angiographic findings,...

journal_title：Annals of nuclear medicine

authors： Nakajima K,Okuda K,Watanabe S,Matsuo S,Kinuya S,Toth K,Edenbrandt L

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:The potential of positron emission tomography/computed tomography using 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM PET/CT), which was originally developed as a hypoxic tracer, to predict therapeutic resistance and prognosis has been reported in various cancers. Our purpose was to investigate pr...

journal_title：Annals of nuclear medicine

authors： Toriihara A,Ohtake M,Tateishi K,Hino-Shishikura A,Yoneyama T,Kitazume Y,Inoue T,Kawahara N,Tateishi U

更新日期：2018-05-01 00:00:00

abstract：AIM:The aim of the study was to compare the kinetic analysis of 18F-labeled choline (FCH) uptake with static analysis and clinicopathological parameters in patients with newly diagnosed prostate cancer (PC). MATERIALS AND METHODS:Sixty-one patients were included. PSA was performed few days before FCH PET/CT. Gleason s...

journal_title：Annals of nuclear medicine

authors： Palard-Novello X,Blin AL,Bourhis D,Garin E,Salaün PY,Devillers A,Querellou S,Bourguet P,Le Jeune F,Saint-Jalmes H

更新日期：2018-05-01 00:00:00

abstract：:We present a comprehensive review of Neuroendocrine Tumors (NET) and the current and developing imaging and therapeutic modalities for NET with emphasis on Nuclear Medicine modalities. Subsequently, nanotechnology and its emerging role in cancer management, especially NET, are discussed. The article is both educative ...

journal_title：Annals of nuclear medicine

authors： Arora G,Bandopadhyaya G

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Image segmentation is an essential step in quantifying the extent of reduced or absent lung function. The aim of this study is to develop and validate a new tool for automatic segmentation of lungs in ventilation and perfusion SPECT images and compare automatic and manual SPECT lung segmentations with referen...

journal_title：Annals of nuclear medicine

authors： Cheimariotis GA,Al-Mashat M,Haris K,Aletras AH,Jögi J,Bajc M,Maglaveras N,Heiberg E

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:In mCRPC patients treated with 223Ra, a major issue is the validation of reliable prognostic and predictive biomarkers to maximize clinical benefit and minimize toxicities and costs. Bearing in mind how changes in tALP did not meet statistical requirements as surrogate marker for survival, aim of this single-...

journal_title：Annals of nuclear medicine

authors： Frantellizzi V,Farcomeni A,Follacchio GA,Pacilio M,Pellegrini R,Pani R,De Vincentis G

更新日期：2018-02-01 00:00:00

abstract：RATIONALE:Myocardial perfusion SPECT is a commonly performed, well established, clinically useful procedure for the management of patients with coronary artery disease. However, the attenuation of photons from myocardium impacts the quantification of infarct sizes. CT-Attenuation Correction (AC) potentially resolves th...

journal_title：Annals of nuclear medicine

authors： Kroiss AS,Nekolla SG,Dobrozemsky G,Grubinger T,Shulkin BL,Schwaiger M

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess I-131 biokinetics in thyroid cancer and remnant tissue in patients with differentiated thyroid cancer using whole-body scan (WBS) and SPECT images acquired after I-131 therapy. The influence of thyroid stimulating hormone (TSH) stimulation method on the kinetics was also ev...

journal_title：Annals of nuclear medicine

authors： Hong CM,Kim CY,Son SH,Jung JH,Lee CH,Jeong JH,Jeong SY,Lee SW,Lee J,Ahn BC

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:Although dual-energy (DE) acquisition with conventional 201Tl myocardial perfusion SPECT has several advantages such as improved attenuation of the inferior wall and increased acquisition counts, the characteristics of IQ-SPECT have not been fully evaluated. We evaluate the difference of characteristics betw...

journal_title：Annals of nuclear medicine

authors： Shibutani T,Onoguchi M,Yoneyama H,Konishi T,Matsuo S,Nakajima K,Kinuya S

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:One of the major causes of diabetes and obesity is abnormality in glucose metabolism and glucose uptake in the muscle and adipose tissue based on an insufficient action of insulin. Therefore, many of the drug discovery programs are based on the concept of stimulating glucose uptake in these tissues. Improveme...

journal_title：Annals of nuclear medicine

authors： Ishino S,Sugita T,Kondo Y,Okai M,Tsuchimori K,Watanabe M,Mori I,Hosoya M,Horiguchi T,Kamiguchi H

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:4-Benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-B-IBSP, has shown high-binding affinity to both sigma (σ) receptors in our previous work. In current study, radiolabeling and preclinical evaluation of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine, 4-B-[125I]IBSP, in human ductal breast carcinoma (T47D) cel...

journal_title：Annals of nuclear medicine

authors： Sadeghzadeh M,Alirezapour B,Charkhlooie GA,Baghery MK,Khorouti A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Aortic knob width on chest radiography represents the extent of aortic dialation and tortuosity of the aortic arch. We tested the hypothesis that aortic knob width reflected left ventricular (LV) diastolic function assessed by gated myocardial perfusion single photon emission computed tomography (SPECT) in p...

journal_title：Annals of nuclear medicine

authors： Kurisu S,Higaki T,Sumimoto Y,Ikenaga H,Watanabe N,Ishibashi K,Dohi Y,Fukuda Y,Kihara Y

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:An iterative reconstruction method in combination with resolution recovery, attenuation and scatter corrections (IR-RASC) can improve image quality. It, however, is undetermined whether this technique can improve the detection of coronary artery disease (CAD) when automated quantitative analysis is used. This...

journal_title：Annals of nuclear medicine

authors： Chono T,Onoguchi M,Shibutani T,Hashimoto A,Nakata T,Yama N,Tsuchihashi K,Hatakenaka M

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:We evaluated the relationships between coronary flow reserve (CFR) and relative flow reserve (RFR) measured by N-13 ammonia positron emission tomography (PET) for characterization of epicardial coronary artery disease (CAD). METHODS:Sixty-nine consecutive stable angina patients underwent N-13 ammonia PET, co...

journal_title：Annals of nuclear medicine

authors： Cho SG,Park KS,Kim J,Kang SR,Song HC,Kim JH,Cho JY,Hong YJ,Jabin Z,Park HJ,Jeong GC,Kwon SY,Paeng JC,Kim HS,Min JJ,Garcia EV,Bom HH

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:In the initial assessment of thyroid nodules, thyrotropin (TSH) has very low sensitivity for assessing functional thyroid nodules (FTNs). The false negativity in FTNs and the false positivity in non-FTNs misinterpreted by TSH will raise unnecessary assessment costs. Therefore, the aim of this study is to expl...

journal_title：Annals of nuclear medicine

authors： Cai H,Qiao Y,Huang X,Sun M,Luo Q,Yuan X,Yang Y,Mao W,Lv Z

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:We investigated the prevalence and clinical significance of incidental focal 18F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT. METHODS:From a total of 32,834 patients who underwent 18F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were select...

journal_title：Annals of nuclear medicine

authors： Park SB,Choi JY,Kim HJ,Kim HJ,Lee KH,Kim BT

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to establish the optimal regions of interest (ROIs) in anatomically normalized I-123 FP-CIT SPECT images for the quantification of dopamine transporter binding. METHODS:The subjects comprised 16 normal controls and 14 Parkinsonian patients. All of the normal control subjects underwen...

journal_title：Annals of nuclear medicine

authors： Nonokuma M,Kuwabara Y,Hida K,Tani T,Takano K,Yoshimitsu K

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine whether (11)C-hydroxyephedrine ((11)C-HED) can predict adverse events including all-cause death in Japanese patients with left ventricular (LV) dysfunction. BACKGROUND:Although (11)C-HED PET has been used to assess cardiac sympathetic innervation in various disease con...

journal_title：Annals of nuclear medicine

authors： Fujita W,Matsunari I,Aoki H,Nekolla SG,Kajinami K

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Exact classifying between malignant and benign tumors in the parotid gland is important because the cancer has relatively poor prognosis. There have been several studies that F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) can differentiate between malignant and benign parotid gland tumors. H...

journal_title：Annals of nuclear medicine

authors： Kim BS,Kim SJ,Pak K

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To compare the diagnostic accuracy of whole-body PET/CT and integrated PET/MR in relation to the total scan time durations. METHODS:One hundred and twenty-three (123) patients (40 males and 83 females; mean age 59.6 years; range 20-83 years) with confirmed primary cancer and clinical suspicion of metastatic di...

journal_title：Annals of nuclear medicine

authors： Ishii S,Shimao D,Hara T,Miyajima M,Kikuchi K,Takawa M,Kumamoto K,Ito H,Shishido F

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:In clinical practice, measurement of the rCBF has mainly been conducted by I-123-N-isopropyl-p-iodoamphetamine ((123)I-IMP) SPECT using the microsphere (MS) method, with continuous arterial blood sampling. While several non-invasive (123)I-IMP quantification methods have been developed, their accuracy has bee...

journal_title：Annals of nuclear medicine

authors： Ofuji A,Mimura H,Yamashita K,Takaki A,Sone T,Ito S

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) and PET/computed tomography (PET/CT) have had a considerable impact on the detection of various malignancies. PET and PET/CT are minimally invasive methods that can provide whole-body imaging at one time. Therefore, an FDG-PET cancer scre...

journal_title：Annals of nuclear medicine

authors： Yamamoto Y,Tasaki Y,Kuwada Y,Ozawa Y,Inoue T

更新日期：2016-02-01 00:00:00

abstract：AIM:To investigate the diagnostic performance of early acquisition compared to late imaging for the detection of local recurrence of prostate cancer by means of ¹⁸F-FCH PET/CT. MATERIALS AND METHODS:99 patients with radical prostatectomy (mean PSA 3.9 ± 5.03) were subjected to early dynamic PET/CT acquisition of the p...

journal_title：Annals of nuclear medicine

authors： Di Biagio D,Chiaravalloti A,Tavolozza M,Abbatiello P,Schillaci O

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:A complication after spinal fusion surgery is pseudarthrosis, but its radiological diagnosis is of limited value. (18)F-fluoride PET with its ability to assess bone metabolism activity could be of value. The goal of this study was to assess the clinical feasibility of calculating the static standardized uptak...

journal_title：Annals of nuclear medicine

authors： Peters MJ,Wierts R,Jutten EM,Halders SG,Willems PC,Brans B

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Technetium etarfolatide ((99m)Tc-EF) is a radioactive diagnostic imaging agent that was developed to assess the expression of folate receptors in tumors. Administering folic acid prior to the administration of (99m)Tc-EF has been shown to improve SPECT images. Here, we conducted a phase I clinical trial to as...

journal_title：Annals of nuclear medicine

authors： Yamada Y,Nakatani H,Yanaihara H,Omote M

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate whether total lesion glycolysis (TLG) and metabolic tumor volume (MTV) measured by ¹⁸F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) could predict the aggressiveness and lymph node metastasis (LNM) in patients with incid...

journal_title：Annals of nuclear medicine

authors： Kim BH,Kim SJ,Kim K,Kim H,Kim SJ,Kim WJ,Jeon YK,Kim SS,Kim YK,Kim IJ

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Estimation of myocardial blood flow (MBF) and coronary flow reserve (CFR) by SPECT myocardial perfusion imaging (MPI) remains challenging. Our aim was to approximate MBF and CFR by quantifying the absolute Tc-99m tetrofosmin retention in the myocardium via gated-SPECT/CT MPI. METHODS:Tracer retention was cal...

journal_title：Annals of nuclear medicine

authors： Apostolopoulos DJ,Kaspiri A,Spyridonidis T,Patsouras N,Savvopoulos CA,Davlouros P,Vassilakos PJ,Alexopoulos D

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:This study investigated the prognostic value of preoperative breast-specific gamma imaging (BSGI) uptake measured by a semi-quantitative method in invasive ductal carcinoma (IDC). METHODS:One hundred and sixty-two women with IDC who underwent preoperative BSGI were retrospectively enrolled. The tumor-to-nor...

journal_title：Annals of nuclear medicine

authors： Yoon HJ,Kim Y,Chang KT,Kim BS

更新日期：2015-08-01 00:00:00

abstract：AIM:The presence of an elevated copper concentration in cancer cells may be potentially used to differentiate healthy from transformed cells. In this study, we aimed to look at the possible role of (64)CuCl2 PET/CT in staging of patients with prostate cancer (PC). METHODS:Seven patients affected by histologically conf...

journal_title：Annals of nuclear medicine

authors： Capasso E,Durzu S,Piras S,Zandieh S,Knoll P,Haug A,Hacker M,Meleddu C,Mirzaei S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Attenuation correction (AC) on nuclear images of non-uniform domains is generally performed by a change of the computed tomography (CT) values to μ values, which are then inserted as components into the detection probability of iterative reconstruction techniques (OS-EM Iterative AC). We established an AC tec...

journal_title：Annals of nuclear medicine

authors： Nakamura Y,Tomiguchi S

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:Nowadays, the number of primary studies on fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has been increasing rapidly. Thus, we updated meta-analysis to evaluate the test performance of FDG PET/CT for nodal staging in non-small cell lung cancer (NSCLC) including the most r...

journal_title：Annals of nuclear medicine

authors： Pak K,Park S,Cheon GJ,Kang KW,Kim IJ,Lee DS,Kim EE,Chung JK

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Respiratory motion causes loss of image quality and inaccuracy of quantification in oncologic positron emission tomography (PET) imaging. This study introduces a bioimpedance-based gating method for compensation of respiratory motion artefacts. METHODS:The bioimpedance-based respiratory gating method was stu...

journal_title：Annals of nuclear medicine

authors： Koivumäki T,Teuho J,Teräs M,Vauhkonen M,Hakulinen MA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:In a diagnostic context, determination of absorbed dose is required before the introduction of a new radiopharmaceutical to the market to obtain marketing authorization from the relevant agencies. In this work, the absorbed dose of [67 Ga]-ethylenecysteamine cysteine [(67 Ga)ECC] to human organs was determine...

journal_title：Annals of nuclear medicine

authors： Shanehsazzadeh S,Yousefnia H,Lahooti A,Zolghadri S,Jalilian AR,Afarideh H

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Positron emission tomography (PET) angiography utilizes early dynamic PET acquisitions for depiction of the arterial vasculature. The aim of this study was to assess image quality and to evaluate feasibility of F-18 FDG PET angiography of the abdominal arteries. METHODS:Twenty-seven patients were included in...

journal_title：Annals of nuclear medicine

authors： Drescher R,Freesmeyer M

更新日期：2015-02-01 00:00:00